Anti-HMGCS2 Antibody (C-term)

Catalog number A04371-1-80ul

Price for A04371-1-80ul

Size / count 80 µL

About this product

Boster Bio Anti-HMGCS2 Antibody (C-term) (Catalog # A04371-1) . Tested in WB, Flow Cytometry, IHC-P application (s) . This antibody reacts with Human.

Specifications

Catalog number: A04371-1-80ul
Size / count: 80 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: HMGCS2 belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting.
Synonyms: Hydroxymethylglutaryl-CoA synthase, mitochondrial, HMG-CoA synthase, 3-hydroxy-3-methylglutaryl coenzyme A synthase, HMGCS2
Gene Name: HMGCS2
UniProt: P54868
Host: Rabbit
Reactivity: Human
Immunogen: This HMGCS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 478-508 amino acids from the C-terminal region of human HMGCS2.
Clonality: Polyclonal
Tissue Specificity: Expression in liver is 200-fold higher than in any other tissue. Low expression in colon, kidney, testis, and pancreas Very low expression in heart and skeletal muscle (PubMed:7893153, PubMed:21952825, PubMed:16940161) . Not detected in brain (PubMed:21952825) .
Applications: WB, Flow Cytometry, IHC-P
Field of Research: Cancer, Cardiovascular, Metabolism, Signal Transduction, Mitochondria
Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function: Catalyzes the first irreversible step in ketogenesis, condensing acetyl-CoA to acetoacetyl-CoA to form HMG-CoA, which is converted by HMG-CoA reductase (HMGCR) into mevalonate.
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight: 56635 Da
Subcellular Location: Mitochondrion {ECO:0000250|UniProtKB:P22791}.
Isotype: Rabbit IgG
Contents: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-HMGCS2 Antibody (C-term)?

The catalog number for Anti-HMGCS2 Antibody (C-term) is A04371-1-80ul.

What sizes are available for Anti-HMGCS2 Antibody (C-term)?

Anti-HMGCS2 Antibody (C-term) is available in the following size(s): 80 µL.

Is Anti-HMGCS2 Antibody (C-term) in stock?

Anti-HMGCS2 Antibody (C-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-HMGCS2 Antibody (C-term)?

The safety data sheet for Anti-HMGCS2 Antibody (C-term) is available here: https://www.bosterbio.com/msds?sku=A04371-1.

What is Anti-HMGCS2 Antibody (C-term) used for?

Boster Bio Anti-HMGCS2 Antibody (C-term) (Catalog # A04371-1) . Tested in WB, Flow Cytometry, IHC-P application (s) . This antibody reacts with Human.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.