Anti-RFX1 Antibody

About this product

Boster Bio Anti-RFX1 Antibody (Catalog # A04392) . Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human.

Specifications

Catalog number

A04392

Size / count

0.1 mg

Dry ice

No

Hazardous

No

Discontinued

No

Background

RFX1 is a member of the regulatory factor X protein family, which are transcription factors that contain a highly-conserved winged helix DNA binding domain and the D region found in the C-terminal part of these proteins which facilitates dimerization (1,2) . RFX1 is structurally related to regulatory factors X2, X3, X4, and X5 (3) . RFX1 is a regulatory factor essential for MHC class II genes expression and can bind to an inverted repeat that is required for expression of hepatitis B virus genes (4) . Recent study identifies RFX1 may play a tumor suppressor role in HCC as autophagy mediator (5) .

Synonyms

RFX, MHC class II regulatory factor RFX, MHC class II regulatory factor RFX1, enhancer factor C, EFC, trans-acting regulatory factor 1, transcription factor RFX1

Gene Name

RFX1

UniProt

P22670

Host

Rabbit

Reactivity

Human

Cross Reactivity

RFX1 antibody is human specific. At least two isoforms of RFX1 are known to exist; this antibody will detect both isoforms.

Immunogen

RFX1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human RFX1. The immunogen is located within the last 50 amino acids of RFX1.

Clonality

Polyclonal

Applications

ELISA, WB, ICC, IF

Field of Research

Immunology, Autophagy

Purification

RFX1 antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Regulatory factor essential for MHC class II genes expression. Binds to the X boxes of MHC class II genes. Also binds to an inverted repeat (ENH1) required for hepatitis B virus genes expression and to the most upstream element (alpha) of the RPL30 promoter.

Storage Conditions

RFX1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Observed Molecular Weight

104758 MW

Gene Name Synonym

Regulatory factor X, 1 (influences HLA class II expression)

Subcellular Location

Nucleus.

Prediction Reactivity

Mouse

Protein Name

Regulatory factor X, 1 (influences HLA class II expression)

Isotype

IgG

Contents

RFX1 antibody is supplied in PBS containing 0.02% sodium azide.