Anti-Contactin-1 CNTN1 Antibody

About this product

Boster Bio Anti-Contactin-1 CNTN1 Antibody catalog # A04538. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

A04538

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Contactin-1; Glycoprotein gp135; Neural cell surface protein F3; CNTN1

Gene Name

CNTN1

UniProt

Q12860

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding Human CNTN1.

Clonality

Polyclonal

Tissue Specificity

Strongly expressed in brain and in neuroblastoma and retinoblastoma cell lines. Lower levels of expression in lung, pancreas, kidney and skeletal muscle.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth (By similarity) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

113320 MW

Applications Notes

WB: 1:500-1:1000

Gene Name Synonym

Contactin-1

Subcellular Location

Isoform 1: Cell membrane; Lipid-anchor, GPI- anchor; Extracellular side.

Protein Name

Contactin-1

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2