Anti-COL9A1 Antibody (Center)

About this product

Boster Bio Anti-COL9A1 Antibody (Center) (Catalog # A04554-2) . Tested in IHC-P, WB application (s) . This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

A04554-2-80ul

Size / count

80 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

COL9A1 is one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in the COL9A1 gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects.

Synonyms

Collagen alpha-1 (IX) chain, COL9A1

Gene Name

COL9A1

UniProt

P20849

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

This COL9A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 428-456 amino acids from the Central region of human COL9A1.

Clonality

Polyclonal

Applications

IHC-P, WB

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Structural component of hyaline cartilage and vitreous of the eye.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

91869 Da

Subcellular Location

Secreted, extracellular space, extracellular matrix

Prediction Reactivity

Mouse

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.