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Product details

Anti-MARK1/2/3/4 (N211) Antibody

Catalog number A04564

Price for A04564

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Size / count 100 µL

About this product

Boster Bio Anti-MARK1/2/3/4 (N211) Antibody catalog # A04564. Tested in IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number
A04564
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
Synonyms
Serine/threonine-protein kinase MARK1;2.7.11.1;2.7.11.26; MAP/microtubule affinity-regulating kinase 1; PAR1 homolog c; Par-1c; Par1c; MARK1
Gene Name
MARK1
UniProt
Q9P0L2/Q7KZI7/P27448/Q96L34
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 180-230 of Human MARK1.
Clonality
Polyclonal
Tissue Specificity
Highly expressed in heart, skeletal muscle, brain, fetal brain and fetal kidney.
Applications
IHC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Serine/threonine-protein kinase (PubMed:23666762) . Involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2 and MAP4. Phosphorylates the microtubule- associated protein MAPT/TAU (PubMed:23666762) . Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
89003 MW
Gene Name Synonym
Serine/threonine-protein kinase MARK1
Subcellular Location
Cell membrane
Protein Name
Serine/threonine-protein kinase MARK1
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-MARK1/2/3/4 (N211) Antibody?

The catalog number for Anti-MARK1/2/3/4 (N211) Antibody is A04564.

What sizes are available for Anti-MARK1/2/3/4 (N211) Antibody?

Anti-MARK1/2/3/4 (N211) Antibody is available in the following size(s): 100 µL.

Is Anti-MARK1/2/3/4 (N211) Antibody in stock?

Anti-MARK1/2/3/4 (N211) Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-MARK1/2/3/4 (N211) Antibody?

The safety data sheet for Anti-MARK1/2/3/4 (N211) Antibody is available here: https://www.bosterbio.com/msds?sku=A04564.

What is Anti-MARK1/2/3/4 (N211) Antibody used for?

Boster Bio Anti-MARK1/2/3/4 (N211) Antibody catalog # A04564. Tested in IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

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