Anti-TORC3 CRTC3 Monoclonal Antibody

About this product

Boster Bio Anti-TORC3 CRTC3 Monoclonal Antibody catalog # A04568. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Monkey.

Specifications

Catalog number

A04568

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

CREB-regulated transcription coactivator 3; Transducer of regulated cAMP response element-binding protein 3; TORC-3; Transducer of CREB protein 3; CRTC3; TORC3

Gene Name

CRTC3

UniProt

Q6UUV7

Host

Mouse

Reactivity

Human, Monkey

Immunogen

Purified recombinant fragment of human TORC3 expressed in E. Coli.

Clonality

Monoclonal

Clone

Clone: 5G9

Tissue Specificity

Predominantly expressed in B and T lymphocytes. Highest levels in lung. Also expressed in brain, colon, heart, kidney, ovary, and prostate. Weak expression in liver, pancreas, muscle, small intestine, spleen and stomach. .

Applications

WB, IHC, IF, ELISA

Purification

Affinity purification

Sensitivity

>5000 cells

Concentration

1 mg/mL

Form

Liquid

Function

Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

66959 MW

Gene Name Synonym

CREB-regulated transcription coactivator 3

Subcellular Location

Nucleus . Cytoplasm . Appears to be mainly nuclear. .

Isotype

IgG1

Contents

Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.