Anti-CD3G Antibody

Catalog number A04853

Price for A04853

Size / count 100 µL

About this product

Boster Bio Anti-CD3G Antibody catalog # A04853. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: A04853
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: T-cell surface glycoprotein CD3 gamma chain; T-cell receptor T3 gamma chain; CD3g; CD3G; T3G
Gene Name: CD3G
UniProt: P09693
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: A synthetic peptide corresponding to residues in Human CD3G.
Clonality: Polyclonal
Applications: WB
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration: 1 mg/mL
Form: Liquid
Function: Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways (PubMed:2470098) . In addition to this role of signal transduction in T-cell activation, CD3G plays an essential role in the dynamic regulation of TCR expression at the cell surface (PubMed:8187769) . Indeed, constitutive TCR cycling is dependent on the di-leucine-based (diL) receptor-sorting motif present in CD3G.
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight: 20469 MW
Applications Notes: WB: 1:500-1:1000
Gene Name Synonym: T-cell surface glycoprotein CD3 gamma chain
Subcellular Location: Cell membrane
Protein Name: T-cell surface glycoprotein CD3 gamma chain
Contents: Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-CD3G Antibody?

The catalog number for Anti-CD3G Antibody is A04853.

What sizes are available for Anti-CD3G Antibody?

Anti-CD3G Antibody is available in the following size(s): 100 µL.

Is Anti-CD3G Antibody in stock?

Anti-CD3G Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-CD3G Antibody?

The safety data sheet for Anti-CD3G Antibody is available here: https://www.bosterbio.com/msds?sku=A04853.

What is Anti-CD3G Antibody used for?

Boster Bio Anti-CD3G Antibody catalog # A04853. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.