Anti-MTCH2 Antibody

About this product

Boster Bio Anti-MTCH2 Antibody (Catalog # A05288) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.

Specifications

Catalog number

A05288

Size / count

0.1 mg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals, suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway.

Synonyms

HSPC032, 2310034D24Rik, 4930539J07Rik, Mitochondrial carrier homolog 2

Gene Name

MTCH2

UniProt

Q791V5

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

MTCH2 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human MTCH2. The immunogen is located within amino acids 80 - 130 of MTCH2.

Clonality

Polyclonal

Tissue Specificity

Highest expression in heart, skeletal muscle and brain. Lower expression in all other tissues.

Applications

ELISA, WB, IHC-P, IF

Field of Research

Apoptosis

Purification

MTCH2 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

The substrate transported is not yet known. Induces mitochondrial depolarization (By similarity) . .

Storage Conditions

MTCH2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Observed Molecular Weight

33499 MW

Gene Name Synonym

Mitochondrial carrier homolog 2 (C. elegans)

Subcellular Location

Mitochondrion inner membrane ; Multi-pass membrane protein .

Prediction Reactivity

Bovine

Protein Name

Mitochondrial carrier homolog 2 (C. elegans)

Isotype

IgG

Contents

MTCH2 Antibody is supplied in PBS containing 0.02% sodium azide.