Anti-EN1 (Engrailed 1) Antibody (N-term)

About this product

Boster Bio Anti-EN1 (Engrailed 1) Antibody (N-term) (Catalog # A05395) . Tested in IF, IHC-P, WB application (s) . This antibody reacts with Human, Mouse.

Specifications

Catalog number

A05395-200ul

Size / count

200 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system.

Synonyms

Homeobox protein engrailed-1, Homeobox protein en-1, Hu-En-1, EN1

Gene Name

EN1

UniProt

Q05925

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This EN1 (Engrailed 1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human EN1 (Engrailed 1) .

Clonality

Polyclonal

Applications

IF, IHC-P, WB

Field of Research

Developmental Biology, Neuroscience, Signal Transduction, Anti-Wnt-Pathway (plus Lgr5) Antibodies

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Required for proper formation of the apical ectodermal ridge and correct dorsal-ventral patterning in the limb.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

40115 Da

Subcellular Location

Nucleus.

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.