Anti-CALCOCO2 Antibody

Catalog number A05876

Price for A05876

Size / count 100 µL

About this product

Boster Bio Anti-CALCOCO2 Antibody catalog # A05876. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: A05876
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Calcium-binding and coiled-coil domain-containing protein 2; Antigen nuclear dot 52 kDa protein; Nuclear domain 10 protein NDP52 ; Nuclear domain 10 protein 52
Gene Name: CALCOCO2
UniProt: Q13137
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant fusion protein of human NDP52 (NP_005822.1) .
Clonality: Polyclonal
Tissue Specificity: Expressed in all tissues tested with highest expression in skeletal muscle and lowest in brain.
Applications: WB, ICC, IF
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration: 1 mg/mL
Form: Liquid
Function: Xenophagy-specific receptor required for autophagy- mediated intracellular bacteria degradation. Acts as an effector protein of galectin-sensed membrane damage that restricts the proliferation of infecting pathogens such as Salmonella typhimurium upon entry into the cytosol by targeting LGALS8- associated bacteria for autophagy (PubMed:22246324) . Initially orchestrates bacteria targeting to autophagosomes and subsequently ensures pathogen degradation by regulating pathogen-containing autophagosome maturation (PubMed:23022382, PubMed:25771791) . Bacteria targeting to autophagosomes relies on its interaction with MAP1LC3A, MAP1LC3B and/or GABARAPL2, whereas regulation of pathogen-containing autophagosome maturation requires the interaction with MAP3LC3C (PubMed:23022382, PubMed:25771791) . May play a role in ruffle formation and actin cytoskeleton organization and seems to negatively regulate constitutive secretion (PubMed:17635994) .
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight: 52254 MW
Gene Name Synonym: Calcium-binding and coiled-coil domain-containing protein 2
Subcellular Location: Cytoplasm, perinuclear region
Protein Name: Calcium-binding and coiled-coil domain-containing protein 2
Contents: Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-CALCOCO2 Antibody?

The catalog number for Anti-CALCOCO2 Antibody is A05876.

What sizes are available for Anti-CALCOCO2 Antibody?

Anti-CALCOCO2 Antibody is available in the following size(s): 100 µL.

Is Anti-CALCOCO2 Antibody in stock?

Anti-CALCOCO2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-CALCOCO2 Antibody?

The safety data sheet for Anti-CALCOCO2 Antibody is available here: https://www.bosterbio.com/msds?sku=A05876.

What is Anti-CALCOCO2 Antibody used for?

Boster Bio Anti-CALCOCO2 Antibody catalog # A05876. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.