Anti-Protein RCC2 RCC2 Antibody

Catalog number A06203

Price for A06203

Size / count 100 µL

About this product

Boster Bio Anti-Protein RCC2 RCC2 Antibody catalog # A06203. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: A06203
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Protein RCC2; RCC1-like protein TD-60
Gene Name: RCC2
UniProt: Q9P258
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to amino acids 470-520 of Human RCC2.
Clonality: Polyclonal
Applications: WB
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration: 1 mg/mL
Form: Liquid
Function: Multifunctional protein that may effect its functions by regulating the activity of small GTPases, such as RAC1 and RALA (PubMed:12919680, PubMed:25074804, PubMed:26158537, PubMed:28869598) . Required for normal progress through the cell cycle, both during interphase and during mitosis (PubMed:23388455, PubMed:12919680, PubMed:26158537) . Required for the presence of normal levels of MAD2L1, AURKB and BIRC5 on inner centromeres during mitosis, and for normal attachment of kinetochores to mitotic spindles (PubMed:12919680, PubMed:26158537) . Required for normal organization of the microtubule cytoskeleton in interphase cells (PubMed:23388455) . Functions as guanine nucleotide exchange factor (GEF) for RALA (PubMed:26158537) . Interferes with the activation of RAC1 by guanine nucleotide exchange factors (PubMed:25074804) . Prevents accumulation of active, GTP-bound RAC1, and suppresses RAC1-mediated reorganization of the actin cytoskeleton and formation of membrane protrusions (PubMed:25074804, PubMed:28869598) . Required for normal cellular responses to contacts with the extracellular matrix of adjacent cells, and for directional cell migration in response to a fibronectin gradient (in vitro) (PubMed:25074804, PubMed:28869598) .
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight: 56085 MW
Applications Notes: WB: 1:500-1:1000
Gene Name Synonym: Protein RCC2
Subcellular Location: Nucleus, nucleolus
Protein Name: Protein RCC2
Contents: Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-Protein RCC2 RCC2 Antibody?

The catalog number for Anti-Protein RCC2 RCC2 Antibody is A06203.

What sizes are available for Anti-Protein RCC2 RCC2 Antibody?

Anti-Protein RCC2 RCC2 Antibody is available in the following size(s): 100 µL.

Is Anti-Protein RCC2 RCC2 Antibody in stock?

Anti-Protein RCC2 RCC2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-Protein RCC2 RCC2 Antibody?

The safety data sheet for Anti-Protein RCC2 RCC2 Antibody is available here: https://www.bosterbio.com/msds?sku=A06203.

What is Anti-Protein RCC2 RCC2 Antibody used for?

Boster Bio Anti-Protein RCC2 RCC2 Antibody catalog # A06203. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.