Anti-UIMC1 Antibody (C-term)

Catalog number A06262-2-80ul

Price for A06262-2-80ul

Size / count 80 µL

About this product

Boster Bio Anti-UIMC1 Antibody (C-term) (Catalog # A06262-2) . Tested in Flow Cytometry, WB application (s) . This antibody reacts with Human.

Specifications

Catalog number: A06262-2-80ul
Size / count: 80 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Plays a central role in the BRCA1-A complex by specifically binding 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs) . The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. Also weakly binds monoubiquitin but with much less affinity than 'Lys-63'-linked ubiquitin. May interact with monoubiquitinated histones H2A and H2B; the relevance of such results is however unclear in vivo. Does not bind Lys-48'-linked ubiquitin. May indirectly act as a transcriptional repressor by inhibiting the interaction of NR6A1 with the corepressor NCOR1.
Synonyms: BRCA1-A complex subunit RAP80, Receptor-associated protein 80, Retinoid X receptor-interacting protein 110, Ubiquitin interaction motif-containing protein 1, UIMC1, RAP80, RXRIP110
Gene Name: UIMC1
UniProt: Q96RL1
Host: Rabbit
Reactivity: Human
Immunogen: This UIMC1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 567-601 amino acids from the C-terminal region of human UIMC1.
Clonality: Polyclonal
Tissue Specificity: Expressed in testis, ovary, thymus and heart. Expressed in germ cells of the testis.
Applications: Flow Cytometry, WB
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Function: 2462747219328070
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight: 79727 Da
Subcellular Location: Nucleus. Note=Localizes at sites of DNA damage at double-strand breaks (DSBs)
Isotype: Rabbit IgG
Contents: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-UIMC1 Antibody (C-term)?

The catalog number for Anti-UIMC1 Antibody (C-term) is A06262-2-80ul.

What sizes are available for Anti-UIMC1 Antibody (C-term)?

Anti-UIMC1 Antibody (C-term) is available in the following size(s): 80 µL.

Is Anti-UIMC1 Antibody (C-term) in stock?

Anti-UIMC1 Antibody (C-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-UIMC1 Antibody (C-term)?

The safety data sheet for Anti-UIMC1 Antibody (C-term) is available here: https://www.bosterbio.com/msds?sku=A06262-2.

What is Anti-UIMC1 Antibody (C-term) used for?

Boster Bio Anti-UIMC1 Antibody (C-term) (Catalog # A06262-2) . Tested in Flow Cytometry, WB application (s) . This antibody reacts with Human.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.