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Product details

Anti-PPP4C Antibody

Catalog number A06390

Price for A06390

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Size / count 100 µL

About this product

Boster Bio Anti-PPP4C Antibody catalog # A06390. Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number
A06390
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
Synonyms
Serine/threonine-protein phosphatase 4 catalytic subunit; PP4C; Pp4;3.1.3.16
Gene Name
PPP4C
UniProt
P60510
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human PPP4C (NP_002711.1) .
Clonality
Polyclonal
Applications
WB, IHC, IP
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF) -alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C- PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair. Dephosphorylates NDEL1 at CDK1 phosphorylation sites and negatively regulates CDK1 activity in interphase (By similarity) . In response to DNA damage, catalyzes RPA2 dephosphorylation, an essential step for DNA repair since it allows the efficient RPA2-mediated recruitment of RAD51 to chromatin.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
35080 MW
Gene Name Synonym
Serine/threonine-protein phosphatase 4 catalytic subunit
Subcellular Location
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein Name
Serine/threonine-protein phosphatase 4 catalytic subunit
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-PPP4C Antibody?

The catalog number for Anti-PPP4C Antibody is A06390.

What sizes are available for Anti-PPP4C Antibody?

Anti-PPP4C Antibody is available in the following size(s): 100 µL.

Is Anti-PPP4C Antibody in stock?

Anti-PPP4C Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-PPP4C Antibody?

The safety data sheet for Anti-PPP4C Antibody is available here: https://www.bosterbio.com/msds?sku=A06390.

What is Anti-PPP4C Antibody used for?

Boster Bio Anti-PPP4C Antibody catalog # A06390. Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

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