Anti-EIF3C Antibody

Catalog number A06470

Price for A06470

Size / count 100 µL

About this product

Boster Bio Anti-EIF3C Antibody catalog # A06470. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: A06470
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Eukaryotic translation initiation factor 3 subunit C
Gene Name: EIF3C
UniProt: Q99613
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant fusion protein of human EIF3C (NP_003743.1) .
Clonality: Polyclonal
Applications: WB, IHC, ICC, IF
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration: 1 mg/mL
Form: Liquid
Function: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773, PubMed:27462815) . The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC) . The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632) . The eIF- 3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773) .
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight: 105344 MW
Gene Name Synonym: Eukaryotic translation initiation factor 3 subunit C
Subcellular Location: Cytoplasm
Protein Name: Eukaryotic translation initiation factor 3 subunit C
Contents: Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-EIF3C Antibody?

The catalog number for Anti-EIF3C Antibody is A06470.

What sizes are available for Anti-EIF3C Antibody?

Anti-EIF3C Antibody is available in the following size(s): 100 µL.

Is Anti-EIF3C Antibody in stock?

Anti-EIF3C Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-EIF3C Antibody?

The safety data sheet for Anti-EIF3C Antibody is available here: https://www.bosterbio.com/msds?sku=A06470.

What is Anti-EIF3C Antibody used for?

Boster Bio Anti-EIF3C Antibody catalog # A06470. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.