Anti-OAZ1 Antibody

Catalog number A06486

Price for A06486

Size / count 100 µL

About this product

Boster Bio Anti-OAZ1 Antibody catalog # A06486. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: A06486
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Ornithine decarboxylase antizyme 1; AZ1; ODC-Az; OAZ1; OAZ
Gene Name: OAZ1
UniProt: P54368
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: A synthetic peptide corresponding to residues in Human OAZ1.
Clonality: Polyclonal
Applications: WB
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration: 1 mg/mL
Form: Liquid
Function: Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome (PubMed:17900240, PubMed:26305948, PubMed:26443277) . Triggers ODC degradation by inducing the exposure of a cryptic proteasome-interacting surface of ODC (PubMed:26305948) . Stabilizes AZIN2 by interfering with its ubiquitination (PubMed:17900240) . Also inhibits cellular uptake of polyamines by inactivating the polyamine uptake transporter. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. Involved in the translocation of AZIN2 from ER-Golgi intermediate compartment (ERGIC) to the cytosol (PubMed:12097147) .
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight: 25406 MW
Applications Notes: WB: 1:500-1:1000
Gene Name Synonym: Ornithine decarboxylase antizyme 1
Protein Name: Ornithine decarboxylase antizyme 1
Contents: Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-OAZ1 Antibody?

The catalog number for Anti-OAZ1 Antibody is A06486.

What sizes are available for Anti-OAZ1 Antibody?

Anti-OAZ1 Antibody is available in the following size(s): 100 µL.

Is Anti-OAZ1 Antibody in stock?

Anti-OAZ1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-OAZ1 Antibody?

The safety data sheet for Anti-OAZ1 Antibody is available here: https://www.bosterbio.com/msds?sku=A06486.

What is Anti-OAZ1 Antibody used for?

Boster Bio Anti-OAZ1 Antibody catalog # A06486. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.