Product details

Anti-PSMD14 Antibody

Catalog number A06584

Price for A06584

Size / count 100 µL

About this product

Boster Bio Anti-PSMD14 Antibody catalog # A06584. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: A06584
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: 26S proteasome non-ATPase regulatory subunit 14;3.4.19.-;26S proteasome regulatory subunit RPN11;26S proteasome-associated PAD1 homolog 1; PSMD14; POH1
Gene Name: PSMD14
UniProt: O00487
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant fusion protein of human PSMD14 (NP_005796.1) .
Clonality: Polyclonal
Tissue Specificity: Widely expressed. Highest levels in heart and skeletal muscle.
Applications: WB, ICC, IF
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration: 1 mg/mL
Form: Liquid
Function: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. The PSMD14 subunit is a metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains within the complex. Plays a role in response to double-strand breaks (DSBs) : acts as a regulator of non- homologous end joining (NHEJ) by cleaving 'Lys-63'-linked polyubiquitin, thereby promoting retention of JMJD2A/KDM4A on chromatin and restricting TP53BP1 accumulation. Also involved in homologous recombination repair by promoting RAD51 loading.
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight: 34577 MW
Gene Name Synonym: 26S proteasome non-ATPase regulatory subunit 14
Protein Name: 26S proteasome non-ATPase regulatory subunit 14
Contents: Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-PSMD14 Antibody?

The catalog number for Anti-PSMD14 Antibody is A06584.

What sizes are available for Anti-PSMD14 Antibody?

Anti-PSMD14 Antibody is available in the following size(s): 100 µL.

Is Anti-PSMD14 Antibody in stock?

Anti-PSMD14 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-PSMD14 Antibody?

The safety data sheet for Anti-PSMD14 Antibody is available here: https://www.bosterbio.com/msds?sku=A06584.

What is Anti-PSMD14 Antibody used for?

Boster Bio Anti-PSMD14 Antibody catalog # A06584. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.