Anti-Collagen XIII alpha1 COL13A1 Antibody

About this product

Boster Bio Anti-Collagen XIII alpha1 COL13A1 Antibody (Catalog# A06702) . Tested in ICC, IF, ELISA applications. This antibody reacts with Human, Mouse.

Specifications

Catalog number

A06702

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

COL13A1; Collagen alpha-1 (XIII) chain; COLXIIIA1

Gene Name

COL13A1

UniProt

Q5TAT6

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A peptide derived from human Collagen XIII alpha1. Immunogen sequence location: 641-690

Clonality

Polyclonal

Tissue Specificity

Widely expressed in both fetal and adult ocular tissues (at protein level) . In the eye, expression is accentuated in the ciliary muscle, optic nerve and the neural retina. In early placenta, localized to fibroblastoid stromal cells of the placental villi, to endothelial cells of developing capillaries and to cells of the cytotrophoblastic columns. Also detected in large decidual cells of the decidual membrane and to stromal cells of the gestational endometrium, but not in the epithelial cells in the endometrial glands. Isoform 10: Expressed in muscle (PubMed:26626625) .

Applications

ICC, IF, ELISA

Field of Research

Collagen, Cytoskeleton/ECM, ECM Proteins, Extracellular Matrix, Signal Transduction

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/mL, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Involved in cell-matrix and cell-cell adhesion interactions that are required for normal development. May participate in the linkage between muscle fiber and basement membrane. May play a role in endochondral ossification of bone and branching morphogenesis of lung. Binds heparin. At neuromuscular junctions, may play a role in acetylcholine receptor clustering (PubMed:26626625) .

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

69950 MW

Gene Name Synonym

Collagen alpha-1 (XIII) chain

Subcellular Location

Cell membrane; Single-pass type II membrane protein. Cell junction, synapse, postsynaptic cell membrane.

Isotype

Rabbit IgG

Contents

PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.