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Product details

Anti-WNK2 Antibody

Catalog number A07048

Price for A07048

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Size / count 100 µL

About this product

Boster Bio Anti-WNK2 Antibody catalog # A07048. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number
A07048
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
Synonyms
Serine/threonine-protein kinase WNK2 ;2.7.11.1
Gene Name
WNK2
UniProt
Q9Y3S1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human WNK2.
Clonality
Polyclonal
Tissue Specificity
Expressed in various cancer cell lines (at protein level) . Predominantly expressed in heart, brain, skeletal muscle and colon.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SLC12A2, SCNN1A, SCNN1B, SCNN1D and SGK1 and inhibits SLC12A5. Negatively regulates the EGF-induced activation of the ERK/MAPK-pathway and the downstream cell cycle progression. Affects MAPK3/MAPK1 activity by modulating the activity of MAP2K1 and this modulation depends on phosphorylation of MAP2K1 by PAK1. WNK2 acts by interfering with the activity of PAK1 by controlling the balance of the activity of upstream regulators of PAK1 activity, RHOA and RAC1, which display reciprocal activity.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
242676 MW
Applications Notes
WB: 1:500-1:1000
Gene Name Synonym
Serine/threonine-protein kinase WNK2
Subcellular Location
Cytoplasm
Protein Name
Serine/threonine-protein kinase WNK2
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-WNK2 Antibody?

The catalog number for Anti-WNK2 Antibody is A07048.

What sizes are available for Anti-WNK2 Antibody?

Anti-WNK2 Antibody is available in the following size(s): 100 µL.

Is Anti-WNK2 Antibody in stock?

Anti-WNK2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-WNK2 Antibody?

The safety data sheet for Anti-WNK2 Antibody is available here: https://www.bosterbio.com/msds?sku=A07048.

What is Anti-WNK2 Antibody used for?

Boster Bio Anti-WNK2 Antibody catalog # A07048. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

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