Anti-GAR1 Antibody

About this product

Boster Bio Anti-GAR1 Antibody catalog # A07049. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

A07049

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

H/ACA ribonucleoprotein complex subunit 1; Nucleolar protein family A member 1; snoRNP protein GAR1; GAR1; NOLA1

Gene Name

GAR1

UniProt

Q9NY12

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human protein at AA range: 110-190

Clonality

Polyclonal

Applications

WB, ELISA

Purification

GAR1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/mL

Form

Liquid

Function

Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

22348 MW

Gene Name Synonym

H/ACA ribonucleoprotein complex subunit 1

Subcellular Location

Nucleus, nucleolus. Nucleus, Cajal body. Also localized to Cajal bodies (coiled bodies) .

Protein Name

H/ACA ribonucleoprotein complex subunit 1

Isotype

IgG

Contents

Liquid form in PBS containing 50% glycerol, and 0.02% sodium azide.