Anti-Nephrocystin-5 IQCB1 Antibody

About this product

Boster Bio Anti-Nephrocystin-5 IQCB1 Antibody catalog # A07108. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse.

Specifications

Catalog number

A07108

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

IQ calmodulin-binding motif-containing protein 1; Nephrocystin-5; p53 and DNA damage-regulated IQ motif protein; PIQ; IQCB1; KIAA0036, NPHP5; OK/SW-cl.85

Gene Name

IQCB1

UniProt

Q15051

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human IQCB1. AA range:431-480

Tissue Specificity

Ubiquitously expressed in fetal and adult tissues. Localized to the outer segments and connecting cilia of photoreceptor cells. Up-regulated in a number of primary colorectal and gastric tumors. .

Applications

WB, IHC, IF, ELISA

Purification

Immunogen affinity purified

Concentration

1 mg/mL

Form

Liquid

Function

Involved in ciliogenesis. The function in an early step in cilia formation depends on its association with CEP290/NPHP6 (PubMed:23446637) . Involved in regulation of the BBSome complex integrity, specifically for presence of BBS2 and BBS5 in the complex, and in ciliary targeting of selected BBSome cargos. May play a role in controlling entry of the BBSome complex to cilia possibly implicating CEP290/NPHP6 (PubMed:25552655) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

68929 MW

Gene Name Synonym

IQ calmodulin-binding motif-containing protein 1

Subcellular Location

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Localization to the centrosome depends on the interaction with CEP290.

Isotype

IgG

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.