Anti-CIR Antibody (N-term)

Catalog number A07268-80ul

Price for A07268-80ul

Size / count 80 µL

About this product

Boster Bio Anti-CIR Antibody (N-term) (Catalog # A07268) . Tested in WB application (s) . This antibody reacts with Human.

Specifications

Catalog number: A07268-80ul
Size / count: 80 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: CIR may modulate splice site selection during alternative splicing of pre-mRNAs. It fegulates transcription and acts as corepressor for RBPSUH. It recruits RBPSUH to the Sin3-histone deacetylase complex (HDAC) and is required for RBPSUH-mediated repression of transcription.
Synonyms: Corepressor interacting with RBPJ 1, CBF1-interacting corepressor, Recepin, CIR1, CIR
Gene Name: CIR1
UniProt: Q86X95
Host: Rabbit
Reactivity: Human
Immunogen: This CIR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-88 amino acids from the N-terminal region of human CIR.
Clonality: Polyclonal
Tissue Specificity: Highly expressed in heart, brain, placenta, liver, skeletal muscle and pancreas.
Applications: WB
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Function: May modulate splice site selection during alternative splicing of pre-mRNAs (By similarity) . Regulates transcription and acts as corepressor for RBPJ. Recruits RBPJ to the Sin3-histone deacetylase complex (HDAC) . Required for RBPJ-mediated repression of transcription.
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight: 52313 Da
Applications Notes: WB: 1:1000
Subcellular Location: Nucleus speckle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes with NEK6 in the centrosome
Isotype: Rabbit IgG
Contents: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-CIR Antibody (N-term)?

The catalog number for Anti-CIR Antibody (N-term) is A07268-80ul.

What sizes are available for Anti-CIR Antibody (N-term)?

Anti-CIR Antibody (N-term) is available in the following size(s): 80 µL.

Is Anti-CIR Antibody (N-term) in stock?

Anti-CIR Antibody (N-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-CIR Antibody (N-term)?

The safety data sheet for Anti-CIR Antibody (N-term) is available here: https://www.bosterbio.com/msds?sku=A07268.

What is Anti-CIR Antibody (N-term) used for?

Boster Bio Anti-CIR Antibody (N-term) (Catalog # A07268) . Tested in WB application (s) . This antibody reacts with Human.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.