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Product details

Anti-CIR Antibody (N-term)

Catalog number A07268-400ul

Price for A07268-400ul

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Size / count 400 µL

About this product

Boster Bio Anti-CIR Antibody (N-term) (Catalog # A07268) . Tested in WB application (s) . This antibody reacts with Human.

Specifications

Catalog number
A07268-400ul
Size / count
400 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
CIR may modulate splice site selection during alternative splicing of pre-mRNAs. It fegulates transcription and acts as corepressor for RBPSUH. It recruits RBPSUH to the Sin3-histone deacetylase complex (HDAC) and is required for RBPSUH-mediated repression of transcription.
Synonyms
Corepressor interacting with RBPJ 1, CBF1-interacting corepressor, Recepin, CIR1, CIR
Gene Name
CIR1
UniProt
Q86X95
Host
Rabbit
Reactivity
Human
Immunogen
This CIR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-88 amino acids from the N-terminal region of human CIR.
Clonality
Polyclonal
Tissue Specificity
Highly expressed in heart, brain, placenta, liver, skeletal muscle and pancreas.
Applications
WB
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
May modulate splice site selection during alternative splicing of pre-mRNAs (By similarity) . Regulates transcription and acts as corepressor for RBPJ. Recruits RBPJ to the Sin3-histone deacetylase complex (HDAC) . Required for RBPJ-mediated repression of transcription.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
52313 Da
Applications Notes
WB: 1:1000
Subcellular Location
Nucleus speckle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes with NEK6 in the centrosome
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-CIR Antibody (N-term)?

The catalog number for Anti-CIR Antibody (N-term) is A07268-400ul.

What sizes are available for Anti-CIR Antibody (N-term)?

Anti-CIR Antibody (N-term) is available in the following size(s): 400 µL.

Is Anti-CIR Antibody (N-term) in stock?

Anti-CIR Antibody (N-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-CIR Antibody (N-term)?

The safety data sheet for Anti-CIR Antibody (N-term) is available here: https://www.bosterbio.com/msds?sku=A07268.

What is Anti-CIR Antibody (N-term) used for?

Boster Bio Anti-CIR Antibody (N-term) (Catalog # A07268) . Tested in WB application (s) . This antibody reacts with Human.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

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