Anti-AKAP 10 (R27) Antibody

About this product

Boster Bio Anti-AKAP 10 (R27) Antibody catalog # A07311. Tested in WB, IHC applications. This antibody reacts with Human.

Specifications

Catalog number

A07311

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

A-kinase anchor protein 10, mitochondrial; AKAP-10; Dual specificity A kinase-anchoring protein 2; D-AKAP-2; Protein kinase A-anchoring protein 10; PRKA10; AKAP10

Gene Name

AKAP10

UniProt

O43572

Host

Rabbit

Reactivity

Human

Immunogen

Synthetic peptide, corresponding to amino acids 1-50 of Human AKAP 10.

Clonality

Polyclonal

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase (By similarity) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

73818 MW

Gene Name Synonym

A-kinase anchor protein 10, mitochondrial

Subcellular Location

Mitochondrion

Protein Name

A-kinase anchor protein 10, mitochondrial

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2