Anti-Tensin-3 TNS3 Antibody

About this product

Boster Bio Anti-Tensin-3 TNS3 Antibody catalog # A07345. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

A07345

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Tensin-3; Tensin-like SH2 domain-containing protein 1; Tumor endothelial marker 6; TNS3; TEM6, TENS1, TPP

Gene Name

TNS3

UniProt

Q68CZ2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 535-580 of Human TNS3.

Clonality

Polyclonal

Tissue Specificity

Expressed in umbilical vein endothelial cells, epithelial cells, and fibroblasts cells (at protein level) . Highly expressed in thyroid, kidney and placenta. Low expression in heart, skeletal muscle, spleen, liver, and lung. Expressed in tumor endothelial cells. Expression seems to be down-regulated in thyroid tumor tissues and in anaplastic carcinomas.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

May play a role in actin remodeling. Involved in the dissociation of the integrin-tensin-actin complex. EGF activates TNS4 and down-regulates TNS3 which results in capping the tail of ITGB1. Seems to be involved in mammary cell migration. May be involved in cell migration and bone development (By similarity) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

155266 MW

Applications Notes

WB: 1:500-1:1000

Gene Name Synonym

Tensin-3

Subcellular Location

Cell junction, focal adhesion

Protein Name

Tensin-3

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2