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Product details

Anti-HSD17B12 Antibody (Center)

Catalog number A07397-1-400ul

Price for A07397-1-400ul

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Size / count 400 µL

About this product

Boster Bio Anti-HSD17B12 Antibody (Center) (Catalog # A07397-1) . Tested in WB, Flow Cytometry, IHC-P application (s) . This antibody reacts with Human.

Specifications

Catalog number
A07397-1-400ul
Size / count
400 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
The enzyme 17-beta hydroxysteroid dehydrogenase-12 (HSD17B12) uses NADPH to reduce 3-ketoacyl-CoA to 3-hydroxyacyl-CoA during the second step of fatty acid elongation.
Synonyms
Estradiol 17-beta-dehydrogenase 12, 17-beta-hydroxysteroid dehydrogenase 12, 17-beta-HSD 12, 3-ketoacyl-CoA reductase, KAR, 131-, HSD17B12
Gene Name
HSD17B12
UniProt
Q53GQ0
Host
Rabbit
Reactivity
Human
Immunogen
This HSD17B12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-155 amino acids from the Central region of human HSD17B12.
Clonality
Polyclonal
Tissue Specificity
Expressed in most tissues tested. Highly expressed in the ovary and mammary. Expressed in platelets
Applications
WB, Flow Cytometry, IHC-P
Field of Research
Cell Biology, Metabolism, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Catalyzes the second of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme has a 3-ketoacyl-CoA reductase activity, reducing 3-ketoacyl-CoA to 3- hydroxyacyl-CoA, within each cycle of fatty acid elongation. Thereby, it may participate in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May also catalyze the transformation of estrone (E1) into estradiol (E2) and play a role in estrogen formation.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
34324 Da
Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein
Prediction Reactivity
Monkey
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-HSD17B12 Antibody (Center)?

The catalog number for Anti-HSD17B12 Antibody (Center) is A07397-1-400ul.

What sizes are available for Anti-HSD17B12 Antibody (Center)?

Anti-HSD17B12 Antibody (Center) is available in the following size(s): 400 µL.

Is Anti-HSD17B12 Antibody (Center) in stock?

Anti-HSD17B12 Antibody (Center) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-HSD17B12 Antibody (Center)?

The safety data sheet for Anti-HSD17B12 Antibody (Center) is available here: https://www.bosterbio.com/msds?sku=A07397-1.

What is Anti-HSD17B12 Antibody (Center) used for?

Boster Bio Anti-HSD17B12 Antibody (Center) (Catalog # A07397-1) . Tested in WB, Flow Cytometry, IHC-P application (s) . This antibody reacts with Human.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

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