Anti-MAGP-2 MFAP5 Antibody

About this product

Boster Bio Anti-MAGP-2 MFAP5 Antibody (Catalog # A07400) . Tested in ELISA, WB applications. This antibody reacts with Human, Chimpanzee.

Specifications

Catalog number

A07400

Size / count

100 µg

Dry ice

Yes

Hazardous

No

Discontinued

No

Background

This antibody is suitable for Cancer, Immunology and Nuclear Signaling research. MAGP-2 (also known as Microfibril-associated glycoprotein 2, MFAP-2, MP25 and Microfibrillar-associated protein 5 precursor) is a secreted, extracellular matrix protein which is a component of the elastin-associated microfibrils. It forms intermolecular disulfide bonds either with other MAGP-2 molecules or with other components of the microfibrils. MAGP-2 is upregulated in some ovarian cancers and is associated with poor survival of ovarian cancer patients.

Synonyms

MAGP-2, MAGP2, MAGP 2, MFAP 5, MFAP5, MFAP-5, MP25, Microfibril associated glycoprotein 2, microfibrillar associated protein 5

Gene Name

MFAP5

UniProt

Q13361

Host

Rabbit

Reactivity

Human, Chimpanzee

Cross Reactivity

No cross reactivity with other proteins.

Immunogen

This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the carboxy terminal end of human MAGP-2 protein.

Clonality

Polyclonal

Applications

ELISA, WB

Field of Research

Angiogenesis, Cancer, Cytoskeleton/ECM, ECM Proteins, Extracellular Matrix, Invasion/Microenvironment, Signal Transduction

Purification

This affinity-purified antibody is directed against human MAGP-2 protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest cross-reactivity with MAGP-2 protein from human and chimpanzee based on 100% homology with the immunizing sequence. Expect partial reactivity with MAGP-2 from mouse, dog and rat sources based on partial (~75%) sequence homology. Reactivity against homologues from other sources is not known.

Concentration

0.95 mg/mL by UV absorbance at 280 nm

Form

Liquid (sterile filtered)

Function

May play a role in hematopoiesis. In the cardiovascular system, could regulate growth factors or participate in cell signaling in maintaining large vessel integrity (By similarity) . Component of the elastin-associated microfibrils (PubMed:8557636) .

Shipping Conditions

Dry Ice Shipping

Storage Conditions

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.

Observed Molecular Weight

19612 MW

Gene Name Synonym

Microfibrillar-associated protein 5

Subcellular Location

Secreted, extracellular space, extracellular matrix.

Prediction Reactivity

Chimpanzee

Isotype

IgG

Contents

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01% (w/v) Sodium Azide