Anti-YY1-associated factor 2 YAF2 Antibody

About this product

Boster Bio Anti-YY1-associated factor 2 YAF2 Antibody catalog # A08678. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

A08678

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

YY1-associated factor 2; YAF2

Gene Name

YAF2

UniProt

Q8IY57

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to residues in Human YAF2.

Clonality

Polyclonal

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Binds to MYC and inhibits MYC-mediated transactivation. Also binds to MYCN and enhances MYCN-dependent transcriptional activation. Increases calpain 2-mediated proteolysis of YY1 in vitro. Component of the E2F6.com-1 complex, a repressive complex that methylates 'Lys-9' of histone H3, suggesting that it is involved in chromatin-remodeling.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

19901 MW

Applications Notes

WB: 1:500-1:1000

Gene Name Synonym

YY1-associated factor 2

Subcellular Location

Nucleus

Protein Name

YY1-associated factor 2

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2