Anti-Emp (E207) MAEA Antibody

About this product

Boster Bio Anti-Emp (E207) MAEA Antibody catalog # A08766. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

A08766

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Macrophage erythroblast attacher; Cell proliferation-inducing gene 5 protein; Erythroblast macrophage protein; Human lung cancer oncogene 10 protein; HLC-10; MAEA; EMP; HLC10, PIG5

Gene Name

MAEA

UniProt

Q7L5Y9

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 178-228 of Human Emp.

Clonality

Polyclonal

Tissue Specificity

Ubiquitous.

Applications

IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Plays a role in erythroblast enucleation and in the development of the mature macrophages. Mediates the attachment of erythroid cell to mature macrophages, in correlation with the presence of MAEA at cell surface of mature macrophages; This MAEA- mediated contact inhibits erythroid cells apoptosis. Participates in erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages. May contribute to nuclear architecture and cells division events.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

45287 MW

Applications Notes

IHC: 1:50-1:200

Gene Name Synonym

Macrophage erythroblast attacher

Subcellular Location

Nucleus matrix

Protein Name

Macrophage erythroblast attacher

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2