Anti-Plxdc2 Antibody

About this product

Boster Bio Anti-Plxdc2 Antibody (Catalog # A08798) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

A08798

Size / count

0.1 mg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Plxdc2, also known as Tumor endothelial marker 7-related (TEM7R) encodes a protein with 57% amino acid identity to TEM7, the most abundant tumor endothelial marker. Plxdc2 is strongly expressed in the endothelial cells of the tumor stroma, but not in the endothelial cells of normal colonic tissue. Plxdc2 is also expressed at high levels in vessels of some normal tissues, with highest expression in muscle and lung. Plxdc2 and TEM7 may be important for tumor angiogenesis in humans. Cortactin was identified as a protein capable of binding to the extracellular region of both TEM7 and Plxdc2, and may provide new opportunities for the delivery of therapeutic and imaging agents to the vessels of solid tumors.

Synonyms

TEM7R, TEM7R, UNQ2514/PRO6003, Plexin domain-containing protein 2, Tumor endothelial marker 7-related protein

Gene Name

PLXDC2

UniProt

Q6UX71

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Plxdc2 antibody was raised against a 18 amino acid synthetic peptide from near the amino terminus of human Plxdc2. The immunogen is located within amino acids 40 - 90 of Plxdc2.

Clonality

Polyclonal

Tissue Specificity

Expressed in the endothelial cells of the stroma but not in the endothelial cells of normal colonic tissue.

Applications

ELISA, WB, IHC-P, IF

Field of Research

Homeostasis

Purification

Plxdc2 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

May play a role in tumor angiogenesis.

Storage Conditions

Plxdc2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Observed Molecular Weight

59583 MW

Gene Name Synonym

Plexin domain containing 2

Subcellular Location

Membrane ; Single-pass type I membrane protein .

Protein Name

Plexin domain containing 2

Isotype

IgG

Contents

Plxdc2 Antibody is supplied in PBS containing 0.02% sodium azide.