Anti-LMCD1 Antibody (C-term)

Catalog number A08888-400ul

Price for A08888-400ul

Size / count 400 µL

About this product

Boster Bio Anti-LMCD1 Antibody (C-term) (Catalog # A08888) . Tested in WB application (s) . This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: A08888-400ul
Size / count: 400 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue- specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity) . Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.
Synonyms: LIM and cysteine-rich domains protein 1, Dyxin, LMCD1
Gene Name: LMCD1
UniProt: Q9NZU5
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: This LMCD1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 316-350 amino acids from the C-terminal region of human LMCD1.
Clonality: Polyclonal
Tissue Specificity: Expressed in the heart (at protein level) . Expressed in many tissues with highest abundance in skeletal muscle
Applications: WB
Field of Research: Neuroscience, Signal Transduction
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Function: Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6- mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity) . Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight: 40833 Da
Applications Notes: WB: 1:1000
Subcellular Location: Cytoplasm. Nucleus. Note=May shuttle between the cytoplasm and the nucleus.
Isotype: Rabbit IgG
Contents: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-LMCD1 Antibody (C-term)?

The catalog number for Anti-LMCD1 Antibody (C-term) is A08888-400ul.

What sizes are available for Anti-LMCD1 Antibody (C-term)?

Anti-LMCD1 Antibody (C-term) is available in the following size(s): 400 µL.

Is Anti-LMCD1 Antibody (C-term) in stock?

Anti-LMCD1 Antibody (C-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-LMCD1 Antibody (C-term)?

The safety data sheet for Anti-LMCD1 Antibody (C-term) is available here: https://www.bosterbio.com/msds?sku=A08888.

What is Anti-LMCD1 Antibody (C-term) used for?

Boster Bio Anti-LMCD1 Antibody (C-term) (Catalog # A08888) . Tested in WB application (s) . This antibody reacts with Human, Mouse, Rat.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.