Anti-PITRM1 Antibody

Catalog number A08969

Price for A08969

Size / count 100 µL

About this product

Boster Bio Anti-PITRM1 Antibody catalog # A08969. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: A08969
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Presequence protease, mitochondrial
Gene Name: PITRM1
UniProt: Q5JRX3
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant fusion protein of human PITRM1 (NP_055704.2) .
Clonality: Polyclonal
Tissue Specificity: Widely expressed. Expressed at higher level in muscle and heart compared to brain, pancreas, liver, lung and placenta.
Applications: WB, ICC, IF
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration: 1 mg/mL
Form: Liquid
Function: Metalloendopeptidase of the mitochondrial matrix that functions in peptide cleavage and degradation rather than in protein processing (PubMed:10360838, PubMed:16849325, PubMed:19196155, PubMed:24931469) . Has an ATP-independent activity (PubMed:16849325) . Specifically cleaves peptides in the range of 5 to 65 residues (PubMed:19196155) . Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference (PubMed:10360838, PubMed:19196155, PubMed:24931469) . Degrades the transit peptides of mitochondrial proteins after their cleavage (PubMed:19196155) . Also degrades other unstructured peptides (PubMed:19196155) . It is also able to degrade amyloid-beta protein 40, one of the peptides produced by APP processing, when it accumulates in mitochondrion (PubMed:16849325, PubMed:24931469) . It is a highly efficient protease, at least toward amyloid-beta protein 40 (PubMed:24931469) . Cleaves that peptide at a specific position and is probably not processive, releasing digested peptides intermediates that can be further cleaved subsequently (PubMed:24931469) .
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight: 117413 MW
Gene Name Synonym: Presequence protease, mitochondrial
Subcellular Location: Mitochondrion matrix
Protein Name: Presequence protease, mitochondrial
Contents: Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-PITRM1 Antibody?

The catalog number for Anti-PITRM1 Antibody is A08969.

What sizes are available for Anti-PITRM1 Antibody?

Anti-PITRM1 Antibody is available in the following size(s): 100 µL.

Is Anti-PITRM1 Antibody in stock?

Anti-PITRM1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-PITRM1 Antibody?

The safety data sheet for Anti-PITRM1 Antibody is available here: https://www.bosterbio.com/msds?sku=A08969.

What is Anti-PITRM1 Antibody used for?

Boster Bio Anti-PITRM1 Antibody catalog # A08969. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.