Anti-IDH3B Antibody

About this product

Boster Bio Anti-IDH3B Antibody catalog # A09433. Tested in WB applications. This antibody reacts with Human, Rat, Mouse.

Specifications

Catalog number

A09433

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial; Isocitric dehydrogenase subunit beta; NAD (+) -specific ICDH subunit beta; IDH3B

Gene Name

IDH3B

UniProt

O43837

Host

Rabbit

Reactivity

Human, Rat, Mouse

Immunogen

A synthetic peptide corresponding to residues in Human IDH3B

Clonality

Polyclonal

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Plays a structural role to facilitate the assembly and ensure the full activity of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

42184 MW

Applications Notes

WB: 1:500-1:1000

Gene Name Synonym

Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial

Subcellular Location

Mitochondrion.

Protein Name

Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2