Anti-3'-5' RNA helicase YTHDC2 YTHDC2 Antibody

Catalog number A09692

Price for A09692

Size / count 100 µL

About this product

Boster Bio Anti-3'-5' RNA helicase YTHDC2 YTHDC2 Antibody catalog # A09692. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: A09692
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: 3'-5' RNA helicase YTHDC2 ;3.6.4.13
Gene Name: YTHDC2
UniProt: Q9H6S0
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant fusion protein of human YTHDC2 (NP_073739.3) .
Clonality: Polyclonal
Tissue Specificity: Expressed in testis (PubMed:29087293) . Not detected in spermatogonia next to the tubule wall but is strongly expressed in spermatocytes, suggesting that it is up-regulated in germ cells upon entry into meiosis (PubMed:29087293) .
Applications: WB
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration: 1 mg/mL
Form: Liquid
Function: 3'-5' RNA helicase that plays a key role in the male and female germline by promoting transition from mitotic to meiotic divisions in stem cells (PubMed:26318451, PubMed:29033321) . Specifically recognizes and binds N6-methyladenosine (m6A) - containing RNAs, a modification present at internal sites of mRNAs and some non-coding RNAs that plays a role in the efficiency of RNA processing and stability (PubMed:26318451, PubMed:29033321) . Essential for ensuring a successful progression of the meiotic program in the germline by regulating the level of m6A-containing RNAs (By similarity) . Acts by binding and promoting degradation of m6A-containing mRNAs: the 3'-5' RNA helicase activity is required for this process and RNA degradation may be mediated by XRN1 exoribonuclease (PubMed:29033321) . Required for both spermatogenesis and oogenesis (By similarity) .
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight: 160248 MW
Applications Notes: WB: 1:500-1:2000
Gene Name Synonym: 3'-5' RNA helicase YTHDC2
Subcellular Location: Cytoplasm
Protein Name: 3'-5' RNA helicase YTHDC2
Contents: Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-3'-5' RNA helicase YTHDC2 YTHDC2 Antibody?

The catalog number for Anti-3'-5' RNA helicase YTHDC2 YTHDC2 Antibody is A09692.

What sizes are available for Anti-3'-5' RNA helicase YTHDC2 YTHDC2 Antibody?

Anti-3'-5' RNA helicase YTHDC2 YTHDC2 Antibody is available in the following size(s): 100 µL.

Is Anti-3'-5' RNA helicase YTHDC2 YTHDC2 Antibody in stock?

Anti-3'-5' RNA helicase YTHDC2 YTHDC2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-3'-5' RNA helicase YTHDC2 YTHDC2 Antibody?

The safety data sheet for Anti-3'-5' RNA helicase YTHDC2 YTHDC2 Antibody is available here: https://www.bosterbio.com/msds?sku=A09692.

What is Anti-3'-5' RNA helicase YTHDC2 YTHDC2 Antibody used for?

Boster Bio Anti-3'-5' RNA helicase YTHDC2 YTHDC2 Antibody catalog # A09692. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.