Anti-P5F1B Antibody (C-term)

About this product

Boster Bio Anti-P5F1B Antibody (C-term) (Catalog # A09763) . Tested in WB, Flow Cytometry application (s) . This antibody reacts with Human.

Specifications

Catalog number

A09763-400ul

Size / count

400 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

This intronless gene was thought to be a transcribed pseudogene of POU class 5 homeobox 1, however, it has been reported that this gene can encode a functional protein. The encoded protein is nearly the same length as and highly similar to the POU class 5 homeobox 1 transcription factor, has been shown to be a weak transcriptional activator and may play a role in carcinogenesis and eye development.

Synonyms

Putative POU domain, class 5, transcription factor 1B, Oct4-pg1, Octamer-binding protein 3-like, Octamer-binding transcription factor 3-like, POU5F1B

Gene Name

POU5F1B

UniProt

Q06416

Host

Rabbit

Reactivity

Human

Immunogen

This P5F1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214-242 amino acids from the C-terminal region of human P5F1B.

Clonality

Polyclonal

Tissue Specificity

Detected at the mRNA level in several cancer tissues (breast, uterine cervix, lung, thyroid gland, esophagus, colon, urinary bladder, and glioma), but absent in normal tissues

Applications

WB, Flow Cytometry

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Shows weak transcriptional activator activity.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

38588 Da

Subcellular Location

Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00530, ECO:0000269|PubMed:18949397}

Prediction Reactivity

Bovine, Mouse, Pig

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.