Anti-H2AFY2 Antibody (Center)

Catalog number A09931-400ul

Price for A09931-400ul

Size / count 400 µL

About this product

Boster Bio Anti-H2AFY2 Antibody (Center) (Catalog # A09931) . Tested in WB application (s) . This antibody reacts with Human.

Specifications

Catalog number: A09931-400ul
Size / count: 400 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.
Synonyms: Core histone macro-H2A2, Histone macroH2A2, mH2A2, H2AFY2, MACROH2A2
Gene Name: MACROH2A2
UniProt: Q9P0M6
Host: Rabbit
Reactivity: Human
Immunogen: This H2AFY2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-169 amino acids from the Central region of human H2AFY2.
Clonality: Polyclonal
Applications: WB
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight: 40058 Da
Applications Notes: WB: 1:1000
Subcellular Location: Nucleus. Chromosome. Note=Enriched in inactive X chromosome chromatin (PubMed:11331621, PubMed:11262398) and in senescence- associated heterochromatin (PubMed:15621527)
Isotype: Rabbit IgG
Contents: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-H2AFY2 Antibody (Center)?

The catalog number for Anti-H2AFY2 Antibody (Center) is A09931-400ul.

What sizes are available for Anti-H2AFY2 Antibody (Center)?

Anti-H2AFY2 Antibody (Center) is available in the following size(s): 400 µL.

Is Anti-H2AFY2 Antibody (Center) in stock?

Anti-H2AFY2 Antibody (Center) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-H2AFY2 Antibody (Center)?

The safety data sheet for Anti-H2AFY2 Antibody (Center) is available here: https://www.bosterbio.com/msds?sku=A09931.

What is Anti-H2AFY2 Antibody (Center) used for?

Boster Bio Anti-H2AFY2 Antibody (Center) (Catalog # A09931) . Tested in WB application (s) . This antibody reacts with Human.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.