Anti-Importin-9 IPO9 Antibody

About this product

Boster Bio Anti-Importin-9 IPO9 Antibody (Catalog# A10216) . Tested in IHC, WB application (s) . This antibody reacts with Mouse, Human.

Specifications

Catalog number

A10216

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Importin-9; Imp9; Ran-binding protein 9; RanBP9; IPO9; IMP9, KIAA1192, RANBP9; HSPC273

Gene Name

IPO9

UniProt

Q96P70

Host

Rabbit

Reactivity

Mouse, Human

Immunogen

A partial length recombinant Importin-9 protein (amino acids 740-1,041)

Clonality

Polyclonal

Applications

IHC, WB

Field of Research

Cell Biology, Cell Cycle, Cell Division, Chromosome Structure, Epigenetics and Nuclear Signaling, Nuclear Import/Export, Nuclear Receptors, Nuclear Signaling Pathways, Protein Trafficking, Signal Transduction

Purification

Protein A Chromatography

Concentration

0.5-1mg/mL, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity) . Mediates the nuclear import of H2B histone (By similarity), RPS7 and RPL18A. Prevents the cytoplasmic aggregation of RPS7 and RPL18A by shielding exposed basic domains. May also import H2A, H3, H4 histones (By similarity), RPL4 and RPL6. .

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Observed Molecular Weight

115963 MW

Gene Name Synonym

Importin-9

Subcellular Location

Cytoplasm. Nucleus.

Protein Name

Importin-9

Isotype

Rabbit IgG

Contents

100 μ g in 200 μ l PBS containing 0.05% BSA and 0.05% sodium azide.