Anti-ATP6V1A Antibody

About this product

Boster Bio Anti-ATP6V1A Antibody catalog # A10401. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

A10401

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

V-type proton ATPase catalytic subunit A; V-ATPase subunit A;7.1.2.2; V-ATPase 69 kDa subunit; Vacuolar ATPase isoform VA68; Vacuolar proton pump subunit alpha; ATP6V1A; ATP6A1, ATP6V1A1, VPP2

Gene Name

ATP6V1A

UniProt

P38606

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human ATP6V1A

Clonality

Polyclonal

Tissue Specificity

High expression in the skin.

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe (2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (PubMed:28296633) . May play a role in neurite development and synaptic connectivity (PubMed:29668857) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

68304 MW

Gene Name Synonym

V-type proton ATPase catalytic subunit A

Subcellular Location

Cytoplasm

Protein Name

V-type proton ATPase catalytic subunit A

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2