Anti-TMBIM1/Recs1 Antibody

About this product

Boster Bio Anti-TMBIM1/Recs1 Antibody (Catalog # A10501) . Tested in ELISA, IHC, WB applications. This antibody reacts with Human.

Specifications

Catalog number

A10501

Size / count

100 µg

Dry ice

Yes

Hazardous

No

Discontinued

No

Background

This antibody is suitable for Cancer, Immunology and Nuclear Signaling research. TMBIM1 (Transmembrane BAX inhibitor motif-containing protein 1) is a member of the 7 TMS (7 transmembrane domains) family of receptors known to mediate the activation of various transcription factors. TMBIM1 is identified as a novel modulator of NF-kB activation. A drosophila homolog of this protein (dNMDA1 with 40% homology to hTMBIM1) is reported to be unregulated during aging and oxidative stress.

Synonyms

TMBIM1, Putative uncharacterized protein TMBIM1, Protein lifeguard 3, Protein RECS1 homolog, Transmembrane BAX inhibitor motif-containing protein 1, LFG3, RECS1, PP1201, PSEC0158

Gene Name

TMBIM1

UniProt

Q969X1

Host

Rabbit

Reactivity

Human

Immunogen

This protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corresponding to the amino terminus of human TMBIM1 protein.

Clonality

Polyclonal

Applications

ELISA, IHC, WB

Field of Research

Cell Biology

Purification

This product was protein A purified from monospecific antiserum by immunoaffinity chromatography using protein A coupled to agarose beads. This antibody is specific for human TMBIM1 protein. A BLAST analysis was used to suggest partial cross-reactivity with TMBIM1 from mouse and rat sources based on ~88% homology with the immunizing sequence. Cross-reactivity with TMBIM1 from other sources has not been determined.

Concentration

1.2 mg/mL by UV absorbance at 280 nm

Form

Liquid (sterile filtered)

Function

Negatively regulates aortic matrix metalloproteinase-9 (MMP9) production and may play a protective role in vascular remodeling.

Shipping Conditions

Dry Ice Shipping

Storage Conditions

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.

Observed Molecular Weight

34607 MW

Gene Name Synonym

Protein lifeguard 3

Subcellular Location

Membrane ; Multi-pass membrane protein. Lysosome membrane. Endosome membrane.

Isotype

IgG

Contents

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01% (w/v) Sodium Azide