Anti-Protein SOGA1 SOGA1 Antibody

About this product

Boster Bio Anti-Protein SOGA1 SOGA1 Antibody (Catalog # A13046) . Tested in ELISA, WB, IF applications. This antibody reacts with Human.

Specifications

Catalog number

A13046

Size / count

0.1 mg

Dry ice

No

Hazardous

No

Discontinued

No

Background

The recently identified protein suppressor of glucose by autophagy protein 1 (SOGA1) has been found to be involved in the regulation of autophagy (1) . SOGA1 is thought to contribute to adiponectin-mediated insulin-dependent inhibition of autophagy during the activation of adenosine monophosphate kinase (AMPK) (1,2) . SOGA1 contains an internal signal peptide that enables the secretion of a circulating fragment of SOGA1, providing a surrogate marker for intracellular SOGA1 levels (2) . Knockdown of SOGA1 elevated glucose production in primary hepatocytes indicates that SOGA1 is an inhibitor of glucose production. It thus might be useful as a novel therapeutic target for diabetes (3) .

Synonyms

SOGA, KIAA0889, C20orf117, SOGA, Protein SOGA1, SOGA family member 1, 80-kDa SOGA fragment

Gene Name

SOGA1

UniProt

O94964

Host

Rabbit

Reactivity

Human

Cross Reactivity

SOGA1 antibody is human specific. At least four isoforms of SOGA1 are known to exist.

Immunogen

SOGA1 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human SOGA. The immunogen is located within the last 50 amino acids of SOGA1 .

Clonality

Polyclonal

Applications

ELISA, WB, IF

Field of Research

Autophagy

Purification

SOGA1 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Regulates autophagy by playing a role in the reduction of glucose production in an adiponectin- and insulin-dependent manner. .

Storage Conditions

SOGA1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Observed Molecular Weight

159760 MW

Gene Name Synonym

Suppressor of glucose, autophagy associated 1

Subcellular Location

C-terminal 80 kDa form: Secreted . Secreted in primary hepatocyte-conditioned media. .

Prediction Reactivity

Mouse

Protein Name

Suppressor of glucose, autophagy associated 1

Isotype

IgG

Contents

SOGA1 Antibody is supplied in PBS containing 0.02% sodium azide.