Anti-Acetyl-NF-E4 (K43) Antibody

About this product

Boster Bio Anti-Acetyl-NF-E4 (K43) Antibody catalog # A14260. Tested in WB, ELISA, IHC applications. This antibody reacts with Human.

Specifications

Catalog number

A14260

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Transcription factor NF-E4; NFE4

Gene Name

NFE4

UniProt

Q86UQ8

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized acetyl-peptide derived from the human NF-E4 around the acetylation site of K43.

Tissue Specificity

Specifically expressed in fetal liver, cord blood and bone marrow. Also expressed in the K562 and HEL cell lines, which constitutively express the fetal globin genes. .

Applications

WB, ELISA, IHC

Purification

Immunogen affinity purified

Sensitivity

>5000 cells

Concentration

1 mg/mL

Form

Liquid

Function

Functions as part of the SSP (stage selector protein) complex, a complex that contributes to the preferential expression of the gamma-gene in fetal erythroid cells by facilitating the interaction of the gamma-globin genes with enhancer elements contained in the locus control region (LCR) . The complex binds to the stage selector element (SSE) in the proximal gamma-globin promoter. In contrast, isoform 2 acts as a repressor of gamma- globin gene expression by preventing NFE2 and RNA polymerase II recruitment to the promoter. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

19019 MW

Gene Name Synonym

Transcription factor NF-E4

Subcellular Location

Nucleus .

Isotype

IgG

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.