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Product details

Anti-CADH1 Antibody

Catalog number M00063-200ul

Price for M00063-200ul

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Size / count 200 µL

About this product

Boster Bio Anti-CADH1 Antibody (Catalog # M00063) . Tested in WB, IHC-P, IF application (s) . This antibody reacts with Human.

Specifications

Catalog number
M00063-200ul
Size / count
200 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.
Synonyms
Cadherin-1, CAM 120/80, Epithelial cadherin, E-cadherin, Uvomorulin, CD324, E-Cad/CTF1, E-Cad/CTF2, E-Cad/CTF3, CDH1, CDHE, UVO
Gene Name
CDH1
UniProt
P12830
Host
Mouse
Reactivity
Human
Immunogen
This CADH1 antibody is generated from a mouse immunized with a recombinat protein between 1-392 amino acids from human CADH1.
Clonality
Monoclonal
Clone
Clone: 1579CT577.150.80
Tissue Specificity
Non-neural epithelial tissues.
Applications
WB, IHC-P, IF
Field of Research
Cancer, Developmental Biology, Signal Transduction, Anti-Wnt-Pathway (plus Lgr5) Antibodies
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Function
1197633311976333
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
97456 Da
Subcellular Location
Cell junction, adherens junction. Cell membrane; Single-pass type I membrane protein. Endosome. Golgi apparatus, trans-Golgi network. Note=Colocalizes with DLGAP5 at sites of cell-cell contact in intestinal epithelial cells. Anchored to actin microfilaments through association with alpha-, beta- and gamma-catenin. Sequential proteolysis induced by apoptosis or calcium influx, results in translocation from sites of cell-cell contact to the cytoplasm Colocalizes with RAB11A endosomes during its transport from the Golgi apparatus to the plasma membrane
Isotype
IgG1, κ
Contents
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-CADH1 Antibody?

The catalog number for Anti-CADH1 Antibody is M00063-200ul.

What sizes are available for Anti-CADH1 Antibody?

Anti-CADH1 Antibody is available in the following size(s): 200 µL.

Is Anti-CADH1 Antibody in stock?

Anti-CADH1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-CADH1 Antibody?

The safety data sheet for Anti-CADH1 Antibody is available here: https://www.bosterbio.com/msds?sku=M00063.

What is Anti-CADH1 Antibody used for?

Boster Bio Anti-CADH1 Antibody (Catalog # M00063) . Tested in WB, IHC-P, IF application (s) . This antibody reacts with Human.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

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