Anti-Transferrin Antibody

About this product

Boster Bio Anti-Transferrin Antibody (Catalog # M00094-2) . Tested in WB, IHC-P, Flow Cytometry application (s) . This antibody reacts with Human.

Specifications

Catalog number

M00094-2-200ul

Size / count

200 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Transferrins are iron binding transport proteins which can bind two Fe (3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.

Synonyms

Serotransferrin, Transferrin, Beta-1 metal-binding globulin, Siderophilin, TF

Gene Name

TF

UniProt

P02787

Host

Rabbit

Reactivity

Human

Immunogen

This Transferrin antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 432-466 amino acids from human Transferrin.

Clonality

Polyclonal

Tissue Specificity

Expressed by the liver and secreted in plasma.

Applications

WB, IHC-P, Flow Cytometry

Field of Research

Cardiovascular, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Transferrins are iron binding transport proteins which can bind two Fe (3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. (Microbial infection) Serves as an iron source for parasite T.brucei (strain 427), which capture TF via its own transferrin receptor ESAG6:ESAG7 and extract its iron for its own use.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

77050 Da

Subcellular Location

Secreted.

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.