Anti-IF4E Antibody

Catalog number M00135-2-400ul

Price for M00135-2-400ul

Size / count 400 µL

About this product

Boster Bio Anti-IF4E Antibody (Catalog # M00135-2) . Tested in WB, IF application (s) . This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: M00135-2-400ul
Size / count: 400 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.
Synonyms: Eukaryotic translation initiation factor 4E, eIF-4E, eIF4E, eIF-4F 25 kDa subunit, mRNA cap-binding protein, EIF4E, EIF4EL1, EIF4F
Gene Name: EIF4E
UniProt: P06730
Host: Mouse
Reactivity: Human, Mouse, Rat
Immunogen: This IF4E antibody is generated from a mouse immunized with a recombinant protein of human IF4E.
Clonality: Monoclonal
Clone: Clone: 1504CT774.14.55
Applications: WB, IF
Field of Research: Viral process, Host-Virus Interaction
Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.
Function: 116062002433528529987188226840102257881316271312225788132998718824335285243352852347107822684010
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight: 25097 Da
Subcellular Location: Cytoplasm, P-body. Cytoplasm. Cytoplasm, Stress granule. Nucleus. Nucleus speckle. Nucleus, nuclear body Note=Interaction with EIF4ENIF1/4E-T is required for localization to processing bodies (P-bodies) (PubMed:16157702, PubMed:24335285, PubMed:25923732) . Imported in the nucleus via interaction with EIF4ENIF1/4E-T via a piggy-back mechanism (PubMed:10856257) Sequestered in the nucleus by EIF4EBP1 and EIF4EBP2 (By similarity) {ECO:0000250|UniProtKB:P63073, ECO:0000269|PubMed:10856257, ECO:0000269|PubMed:16157702, ECO:0000269|PubMed:24335285, ECO:0000269|PubMed:25923732}
Isotype: IgG1, Κ
Contents: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-IF4E Antibody?

The catalog number for Anti-IF4E Antibody is M00135-2-400ul.

What sizes are available for Anti-IF4E Antibody?

Anti-IF4E Antibody is available in the following size(s): 400 µL.

Is Anti-IF4E Antibody in stock?

Anti-IF4E Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-IF4E Antibody?

The safety data sheet for Anti-IF4E Antibody is available here: https://www.bosterbio.com/msds?sku=M00135-2.

What is Anti-IF4E Antibody used for?

Boster Bio Anti-IF4E Antibody (Catalog # M00135-2) . Tested in WB, IF application (s) . This antibody reacts with Human, Mouse, Rat.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.