Anti-SNCA Antibody

About this product

Boster Bio Anti-SNCA Antibody (Catalog # M00215-4) . Tested in WB application (s) . This antibody reacts with Human, Mouse.

Specifications

Catalog number

M00215-4-200ul

Size / count

200 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.

Synonyms

Alpha-synuclein, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, NACP, SNCA, NACP, PARK1

Gene Name

SNCA

UniProt

P37840

Host

Mouse

Reactivity

Human, Mouse

Immunogen

This antibody is generated from a mouse immunized a recombinant protein from human.

Clonality

Monoclonal

Clone

Clone: 1853CT506.24.16

Tissue Specificity

Highly expressed in presynaptic terminals in the central nervous system. Expressed principally in brain

Applications

WB

Field of Research

Neuroscience

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Function

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Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

14460 Da

Applications Notes

WB: 1:2000

Subcellular Location

Cytoplasm. Membrane. Nucleus. Synapse Secreted. Cell projection, axon {ECO:0000250|UniProtKB:O55042}. Note=Membrane-bound in dopaminergic neurons (PubMed:15282274) . Expressed and colocalized with SEPTIN4 in dopaminergic axon terminals, especially at the varicosities (By similarity) . {ECO:0000250|UniProtKB:O55042, ECO:0000269|PubMed:15282274}

Isotype

IgG1, κ

Contents

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.