Anti-Hu CD326 Purified EPCAM Monoclonal Antibody — image 1 of 2

Product details

Anti-Hu CD326 Purified EPCAM Monoclonal Antibody

Catalog number M00276

Price for M00276

Size / count 0.1 mg

About this product

EPCAM Monoclonal Antibody

Specifications

Catalog number: M00276
Size / count: 0.1 mg
Dry ice: No
Hazardous: No
Discontinued: No
Background: CD326 / EpCAM (also known as ESA, EGP40, EGP-2, KSA1/4, CO17-1A, GA733-2, MOC31, Ber-EP4) is a 40 kDa transmembrane glycoprotein serving as adhesion molecule in the basolateral membranes in a variety of epithelial cells. CD326 mediates calcium-independent homotypic cell-cell adhesions. CD326 over-expression has been detected in many epithelial tumours and is often associated with bad prognosis. It has been used for diagnostics of (pre-) malignancies at early stages.
Synonyms: EPCAM, GA733-2, EGP314, KSA, KS 1/4 antigen, Trop-1, M4S1, DIAR5, MIC18, TROP1
Gene Name: EPCAM
UniProt: P16422
Host: Mouse
Reactivity: Human
Immunogen: Small cell lung carcinoma cell line H69. The mouse monoclonal antibody VU-1D9 recognizes an extracellular epitope within EGF-like domain I of CD326 / EpCAM, a marker of epithelial lineages. This antibody strongly stains various normal epithelial cells and carcinomas.
Clonality: Monoclonal
Clone: Clone: VU-1D9
Tissue Specificity: Highly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (ESC) . Levels rapidly diminish as soon as ESC's differentiate (at protein levels) . Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinoma.
Applications: Flow Cytometry, IHC-P, IP, WB, IHC-F, ICC
Purification: Purified by protein-A affinity chromatography.
Concentration: 1 mg/mL
Form: Liquid
Function: May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
Storage Conditions: Store at 2-8°C. Do not freeze.
Observed Molecular Weight: 34932 MW
Gene Name Synonym: Epithelial cell adhesion molecule
Subcellular Location: Lateral cell membrane
Protein Name: Epithelial cell adhesion molecule
Isotype: Mouse IgG1
Contents: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Frequently Asked Questions

What is the catalog number for Anti-Hu CD326 Purified EPCAM Monoclonal Antibody?

The catalog number for Anti-Hu CD326 Purified EPCAM Monoclonal Antibody is M00276.

What sizes are available for Anti-Hu CD326 Purified EPCAM Monoclonal Antibody?

Anti-Hu CD326 Purified EPCAM Monoclonal Antibody is available in the following size(s): 0.1 mg.

Is Anti-Hu CD326 Purified EPCAM Monoclonal Antibody in stock?

Anti-Hu CD326 Purified EPCAM Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-Hu CD326 Purified EPCAM Monoclonal Antibody?

The safety data sheet for Anti-Hu CD326 Purified EPCAM Monoclonal Antibody is available here: https://www.bosterbio.com/msds?sku=M00276.

What is Anti-Hu CD326 Purified EPCAM Monoclonal Antibody used for?

EPCAM Monoclonal Antibody

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.