Anti-SMAD1 Antibody

Catalog number M00728-3-50ul

Price for M00728-3-50ul

Size / count 50 µL

About this product

Boster Bio Anti-SMAD1 Antibody (Catalog # M00728-3) . Tested in WB, IHC-P, IF application (s) . This antibody reacts with Human.

Specifications

Catalog number: M00728-3-50ul
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD) . SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP) -mediated cardiac-specific gene expression.
Synonyms: Mothers against decapentaplegic homolog 1, MAD homolog 1, Mothers against DPP homolog 1, JV4-1, Mad-related protein 1, SMAD family member 1, SMAD 1, Smad1, hSMAD1, Transforming growth factor-beta-signaling protein 1, BSP-1, SMAD1, BSP1, MADH1, MADR1
Gene Name: SMAD1
UniProt: Q15797
Host: Mouse
Reactivity: Human
Immunogen: This SMAD1 antibody is generated from a mouse immunized with a recombinant protein between 20-330 amino acids from human SMAD1.
Clonality: Monoclonal
Clone: Clone: 1356CT119.18.55
Tissue Specificity: Ubiquitous. Highest expression seen in the heart and skeletal muscle
Applications: WB, IHC-P, IF
Field of Research: Cancer, Developmental Biology, Signal Transduction, Stem Cells, Anti-Wnt-Pathway (plus Lgr5) Antibodies
Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.
Function: 93355043366754333667543
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight: 52260 Da
Subcellular Location: Cytoplasm. Nucleus Note=Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4 (PubMed:15647271) . Co-localizes with LEMD3 at the nucleus inner membrane (PubMed:15647271) . Exported from the nucleus to the cytoplasm when dephosphorylated (By similarity) {ECO:0000250|UniProtKB:P70340, ECO:0000269|PubMed:15647271}
Isotype: IgG1, k
Contents: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-SMAD1 Antibody?

The catalog number for Anti-SMAD1 Antibody is M00728-3-50ul.

What sizes are available for Anti-SMAD1 Antibody?

Anti-SMAD1 Antibody is available in the following size(s): 50 µL.

Is Anti-SMAD1 Antibody in stock?

Anti-SMAD1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-SMAD1 Antibody?

The safety data sheet for Anti-SMAD1 Antibody is available here: https://www.bosterbio.com/msds?sku=M00728-3.

What is Anti-SMAD1 Antibody used for?

Boster Bio Anti-SMAD1 Antibody (Catalog # M00728-3) . Tested in WB, IHC-P, IF application (s) . This antibody reacts with Human.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.