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Product details

Anti-SMAD1 Antibody

Catalog number M00728-3-200ul

Price for M00728-3-200ul

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Size / count 200 µL

About this product

Boster Bio Anti-SMAD1 Antibody (Catalog # M00728-3) . Tested in WB, IHC-P, IF application (s) . This antibody reacts with Human.

Specifications

Catalog number
M00728-3-200ul
Size / count
200 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD) . SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP) -mediated cardiac-specific gene expression.
Synonyms
Mothers against decapentaplegic homolog 1, MAD homolog 1, Mothers against DPP homolog 1, JV4-1, Mad-related protein 1, SMAD family member 1, SMAD 1, Smad1, hSMAD1, Transforming growth factor-beta-signaling protein 1, BSP-1, SMAD1, BSP1, MADH1, MADR1
Gene Name
SMAD1
UniProt
Q15797
Host
Mouse
Reactivity
Human
Immunogen
This SMAD1 antibody is generated from a mouse immunized with a recombinant protein between 20-330 amino acids from human SMAD1.
Clonality
Monoclonal
Clone
Clone: 1356CT119.18.55
Tissue Specificity
Ubiquitous. Highest expression seen in the heart and skeletal muscle
Applications
WB, IHC-P, IF
Field of Research
Cancer, Developmental Biology, Signal Transduction, Stem Cells, Anti-Wnt-Pathway (plus Lgr5) Antibodies
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Function
93355043366754333667543
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
52260 Da
Subcellular Location
Cytoplasm. Nucleus Note=Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4 (PubMed:15647271) . Co-localizes with LEMD3 at the nucleus inner membrane (PubMed:15647271) . Exported from the nucleus to the cytoplasm when dephosphorylated (By similarity) {ECO:0000250|UniProtKB:P70340, ECO:0000269|PubMed:15647271}
Isotype
IgG1, k
Contents
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-SMAD1 Antibody?

The catalog number for Anti-SMAD1 Antibody is M00728-3-200ul.

What sizes are available for Anti-SMAD1 Antibody?

Anti-SMAD1 Antibody is available in the following size(s): 200 µL.

Is Anti-SMAD1 Antibody in stock?

Anti-SMAD1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-SMAD1 Antibody?

The safety data sheet for Anti-SMAD1 Antibody is available here: https://www.bosterbio.com/msds?sku=M00728-3.

What is Anti-SMAD1 Antibody used for?

Boster Bio Anti-SMAD1 Antibody (Catalog # M00728-3) . Tested in WB, IHC-P, IF application (s) . This antibody reacts with Human.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

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