Anti-CD55 Antibody

About this product

Boster Bio Anti-CD55 Antibody (Catalog # M00910-1) . Tested in WB application (s) . This antibody reacts with Human.

Specifications

Catalog number

M00910-1-400ul

Size / count

400 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

This gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF) ; binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM) . Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels. Additional, alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq].

Synonyms

Complement decay-accelerating factor, CD55, CD55, CR, DAF

Gene Name

CD55

UniProt

P08174

Host

Mouse

Reactivity

Human

Immunogen

This CD55 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 51-79 amino acids from human CD55.

Clonality

Monoclonal

Clone

Clone: 561CT4.2.3

Tissue Specificity

Expressed on the plasma membranes of all cell types that are in intimate contact with plasma complement proteins. It is also found on the surfaces of epithelial cells lining extracellular compartments, and variants of the molecule are present in body fluids and in extracellular matrix

Applications

WB

Field of Research

Immunology, Viral process, Host-Virus Interaction, Innate Immunity

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Function

752527428657829

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

41400 Da

Applications Notes

WB: 1:100

Subcellular Location

[Isoform 1]: Cell membrane; Single-pass type I membrane protein [Isoform 3]: Secreted [Isoform 5]: Secreted [Isoform 7]: Cell membrane; Lipid-anchor, GPI-anchor

Isotype

IgG1

Contents

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.