Anti-HSPA5 Antibody

About this product

Boster Bio Anti-HSPA5 Antibody (Catalog # M00955-3) . Tested in WB application (s) . This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M00955-3-50ul

Size / count

50 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate.

Synonyms

78 kDa glucose-regulated protein, GRP-78, Endoplasmic reticulum lumenal Ca (2+) -binding protein grp78, Heat shock 70 kDa protein 5, Immunoglobulin heavy chain-binding protein, BiP, HSPA5, GRP78

Gene Name

HSPA5

UniProt

P11021

Host

Mouse

Reactivity

Human, Mouse, Rat

Immunogen

This HSPA5 antibody is generated from a mouse immunized with a recombinant protein between 420-654 amino acids from human HSPA5.

Clonality

Monoclonal

Clone

Clone: 1672CT323.22.82

Applications

WB

Field of Research

Apoptosis

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Function

229401023769672239906682833255515509581953895726045166

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

72333 Da

Applications Notes

WB: 1:20000

Subcellular Location

Endoplasmic reticulum lumen. Melanosome. Cytoplasm {ECO:0000250|UniProtKB:P20029}. Cell surface Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545) . Localizes to the cell surface of epithelial cells in response to high levels of free iron (PubMed:20484814, PubMed:24355926, PubMed:27159390)

Isotype

IgG1, k

Contents

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.