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Product details

Anti-GLS Antibody (C-Term)

Catalog number M01272-1-200ul

Price for M01272-1-200ul

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Size / count 200 µL

About this product

Boster Bio Anti-GLS Antibody (C-Term) (Catalog # M01272-1) . Tested in WB application (s) . This antibody reacts with Human, Mouse.

Specifications

Catalog number
M01272-1-200ul
Size / count
200 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity.
Synonyms
Glutaminase kidney isoform, mitochondrial, GLS, K-glutaminase, L-glutamine amidohydrolase, GLS, GLS1, KIAA0838
Gene Name
GLS
UniProt
O94925
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This GLS antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 555-587 amino acids from human GLS.
Clonality
Polyclonal
Tissue Specificity
Isoform 1 and isoform 3 are detected in brain cortex. Isoform 3 is highly expressed in astrocytoma, ganglioglioma and ependymoma. Isoform 1 is highly expressed in brain and kidney, but not detected in liver. Isoform 3 is highly expressed in heart and pancreas, detected at lower levels in placenta, lung, pancreas and kidney, but is not detected in liver. Isoform 2 is expressed in cardiac and skeletal muscle.
Applications
WB
Field of Research
Metabolism, Neuroscience, Signal Transduction, Mitochondria
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
305758543023972130970188
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
73461 Da
Applications Notes
WB: 1:2000
Subcellular Location
[Isoform 1]: Mitochondrion {ECO:0000250|UniProtKB:P13264}. Cytoplasm, cytosol. Note=The 74-kDa cytosolic precursor is translocated into the mitochondria and processed via a 72-kDa intermediate to yield the mature 68- and 65-kDa subunits {ECO:0000250|UniProtKB:P13264} [Glutaminase kidney isoform, mitochondrial 68 kDa chain]: Mitochondrion matrix {ECO:0000250|UniProtKB:P13264} Note=Produced by the proteolytic processing of the 74-kDa cytosolic precursor. {ECO:0000250|UniProtKB:P13264}
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-GLS Antibody (C-Term)?

The catalog number for Anti-GLS Antibody (C-Term) is M01272-1-200ul.

What sizes are available for Anti-GLS Antibody (C-Term)?

Anti-GLS Antibody (C-Term) is available in the following size(s): 200 µL.

Is Anti-GLS Antibody (C-Term) in stock?

Anti-GLS Antibody (C-Term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-GLS Antibody (C-Term)?

The safety data sheet for Anti-GLS Antibody (C-Term) is available here: https://www.bosterbio.com/msds?sku=M01272-1.

What is Anti-GLS Antibody (C-Term) used for?

Boster Bio Anti-GLS Antibody (C-Term) (Catalog # M01272-1) . Tested in WB application (s) . This antibody reacts with Human, Mouse.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

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